These side effects are less common side effects occurring in about 10-29 of patients receiving femara .
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FEMARA tablets is indicated for first-line treatment azithromycin. of postmenopausal women with hormone receptor-positive or unknownlocally advancedor metastatic breast cancerFEMARA is also indicated for the
The most serious side effects seen with FEMARA are bone effectsfracturesdecreased bone density and osteoporosisand increases in cholesterolOther common side effects seen with FEMARA include joint painnauseaweight decreasevaginal irritationand pain in the extremitiesOther important less commonly reported side effects include blood clotsother cancersstrokeheart attack and endometrial cancer.
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co-administration of femara with tamoxifen, other anti-oestrogens or oestrogen-containing therapies should be avoided as these substances may diminish the pharmacological action of letrozole see section 4.